What could cause an overactive bladder?

Overactive bladder (OAB) is a condition in which individuals have symptoms such as urinary frequency and urgency, nocturia (multiple urinary voids at night), and incontinence. This can become a huge emotional burden for women.



Usually, a combination of factors causes this condition, some possible causes include:

Idiopathic: OAB may arise spontaneously, and the cause is not known

Weak pelvic muscles: Due to stretching in pregnancy and childbirth 

Postmenopausal estrogen deficiency: Decreasing or falling estrogen levels in the blood after menopause can contribute to developing OAB

Overweight: Being overweight puts extra pressure on the bladder and weakens the pelvic floor muscles. 

Alcohol, caffeine, and urinary tract infection can aggravate the condition. 

The first line of treatment is lifestyle or behavioral changes. As we mentioned in our last post, if these initial efforts don’t help enough with the symptoms, additional treatments are available, such as therapy with oral pills. However, due to side effects, many OAB patients discontinue taking tablets and are left without treatment. Click here to read the current treatment guidelines for OAB and Inura’s solution to this unmet medical need! 


About Inura

Inura Medical AG (“Inura”) is a Swiss start-up company with a clear vision to make a difference in women’s health. Inura’s product is an innovative, first-of-a-kind “urethral ovulum” that utilizes a novel route of drug administration to treat diseases of the bladder and lower urinary tract. Inura’s technology results from decades of work in urology by Professor Grant S. Mulholland, a renowned surgeon, academic, and past President of the American Urology Association. The first indication we are addressing with the ovulum is a chronic disease, named overactive bladder (OAB). More details on https://inuramedical.ch/.